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Ark Investment's Cathie Wood Just Sold AMD Shares and Bought Nvidia. Is That the Right Move for Investors?

Written by Geoffrey Seiler for The Motley Fool -> AMD has huge opportunities in inference and agentic AI. Nvidia remains the top AI infrastructure player. Ark Investment's Cathie Wood has made a name for herself as a champion of stocks with potentially disruptive technologies.

Ark Investment's Cathie Wood Just Sold AMD Shares and Bought Nvidia. Is That the Right Move for Investors?
Nasdaq News โ€” 10 June 2026
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Ark Investment's Cathie Wood has made a name for herself as a champion of stocks with potentially disruptive technologies. Her flagship Ark Innovation ETF (NYSEMKT: ARKK) has had mixed results, up 49% over the past year but down 8.7% on average over the last five, as of the end of April.

Nonetheless, when she makes moves, it tends to be notable. Recently, she has been trimming her stake in Advanced Micro Devices (NASDAQ: AMD) while buying shares of rival Nvidia (NASDAQ: NVDA) . Let's see if investors should be following suit.

Will AI create the world's first trillionaire? Our team just released a report on the one little-known company, called an "Indispensable Monopoly" providing the critical technology Nvidia and Intel both need. Continue ยป

While Wood has trimmed her stake in AMD, it remains her fifth-largest position. The stock has quadrupled over the past year, driving its valuation to 35.5 times 2027 analyst estimates. That likely played a role in her recent decision to take some profits.

However, AMD is at the intersection of two powerful artificial intelligence trends that should help power its results going forward. The first is inference , with its graphics processing units (GPUs) well suited to take share. Inference is less technically demanding than training, which Nvidia's CUDA software does best, while its chiplet design packs in more memory, which is important for inference.

The company has locked in two large GPU partnerships and commitments, each worth an estimated $100 billion. In addition, it's believed that Anthropic will use its next-generation chips. After being an afterthought to Nvidia in AI model training, AMD now looks like a strong alternative for inference.

On top of that, the company also has a big opportunity stemming from agentic AI. While GPUs are great at providing the muscle to train AI models and run inference, they aren't good at sequential reasoning or working with outside tools, both of which are needed for AI agents. That job falls to central processing units (CPUs), which work as the brain of a computer. As a result, the ratio of GPUs to CPUs is expected to fall from 8:1 with training to 1:1 with agentic AI.

This is a huge opportunity for AMD, as it is a leader in the data center CPU market, having consistently taken share away from rival Intel . AMD has said this will be a $120 billion market over the next few years, while Nvidia has said it could become a $200 billion market.

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